Programme

Ln Faculty Lectures (L1-L20)
Sn Scholars’ Oral Presentations (S1-S25)
Wn Interactive Workshops, Seminars and Special Presentations (W1-W8)

• 11 June
• 12 June
• 13 June
• 14 June
• 15 June
• 16 June
• 17 June
• 18 June

• Saturday, 11 June
  11:00-17:00	Arrival of Scholars and Faculty at the Certosa di Pontignano Assignment to rooms in the hotel wing of the Certosa. All food during the week will be provided by the restaurant of the Certosa (breakfast, lunch and dinner).
  17:00	Opening Ceremony Anna Maria Aloisi, School Director, Siena, Italy Molteni, sponsor Peter Reeh, Scientific Programme Director, Erlangen, Germany
  	L1 Chronic overlapping pain disorders Emeran A. Mayer (Los Angeles, CA, USA)
  19:30	Apéritif on the terrace
  20:00	Dinner
  21:30	A guided tour through the Certosa, its Chapel, Cloisters and Garden Giancarlo Carli

   

• Sunday, 12 June
  9:00-10:00	L2 The Microbiome-Gut-Brain Axis in Pain Siobhain O’Mahony (Cork, Ireland)
  10:00-10:15	S1 Neural activity and the immune response in the colon Ariel Epouhe (Pittsburgh, PA, USA)
  10:15-10:30	S2 Exploring biopsychosocial mechanisms of abdominal pain in inflammatory bowel disease and irritable bowel syndrome Danielle Huisman (London, United Kingdom)
  10:30-11:00	Coffee break
  11:00-11:15	S3 Unravelling the involvement of the descending serotonergic modulation on the DNIC analgesic paradigm in prolonged joint inflammatory pain Raquel Pereira-Silva (Oporto, Portugal)
  11:15-11:30	S4 Distinct activity of endocannabinoid-hydrolyzing enzymes MAGL and FAAH in key regions of peripheral and central nervous system implicated in migraine Adriana Della Pietra (Kuopio, Finland)
  11:30-12:30	L3 Neuroinflammation and cytokines in spinal hyperexcitability causing joint pain Andrea Ebersberger (Jena, Germany)
  13:00-15:00	Lunch break
  15:00-16:00	L4 Pregnancy and beyond: role of the Microbiome-Gut-Brain Axis Siobhain O’Mahony (Cork, Ireland)
  16:00-16:15	S5 Investigating the mechanisms underpinning the modulation of visceral sensitivity mediated by faecal microbiota transplantation: focus on the interface between the microbiota and the gut Elena Lucarini (Florence, Italy)
  16:15-16:30	S6 Transient receptor potential ankyrin 1 (TRPA1) contributes to mechanical hypersensitivity in a mouse model of endometriosis Mustafa Titiz (Florence, Italy)
  16:30-17:00	Coffee break
  17:00-17:15	S7 Investigating central mechanisms of 3% levomenthol treatment on chemotherapy-induced peripheral neuropathy: a phase II placebo-controlled RCT with embedded (f)MRI Laura Klinkhamer (Edinburgh, United Kingdom)
  17:15-17:30	S8 Activation of putative nociceptors can modulate the immune profile in the gut Kimberly Meerschaert (Boston, MA, USA)
  17:30-18:30	L5 Colonic Pain Models and what they told us Peter Reeh (Erlangen, Germany)
  20:00-21:30	Dinner in the small Cloister

   

• Monday, 13 June
  9:00-10:00	L6 Visceral pain-associated interoception: influence on emotion, affect and cognition Peter Holzer (Graz, Germany)
  10:00-10:15	S9 The role of gut hormone peptide YY in visceral pain Aitak Farzi (Graz, Germany)
  10:15-10:30	S10 Influence of kinesiophobia on corticomotor excitability and its relation to top-down pain inhibition Arnaud Duport (Sherbrooke, Canada / Calais, France)
  10:30-11:00	Coffee break
  11:00-11:15	S11 Identification of trigeminal sensory neuronal types innervating masseter muscle Karen A. Lindquist (San Antonio, TX, USA)
  11:15-11:30	S12 Methylglyoxal-induced effects on axonal properties of human C-fibers Miriam M. Düll (Erlangen, Germany)
  11:30-12:30	L7 Plasticity and redundancy in nociceptive mechanisms John Wood (London, United Kingdom)
  13:00-15:00	Lunch break
  15:00-16:00	L8 Menstrual pain disorders Felice Petraglia (Florence, Italy)
  16:00-16:15	S13 Soy-enriched bread, a pilot study to determine its beneficial effects in menopause Ilenia Casini (Siena, Italy)
  16:15-16:30	S14 Exploring the role of childhood trauma on pain modulation for people with endometriosis Claire E. Lunde (Oxford, United Kingdom)
  16:30-17:00	Coffee break
  17:00-17:15	S15 Altered anterior insula functional connectivity in adolescent and young women with endometriosis-associated pain: a pilot resting-state fMRI study Edina Szabo (Boston, MA, USA)
  17:15-17:30	S16 Altered resting-state functional connectivity between prefrontal and somatosensory cortex after pain response in healthy adults: a pilot functional near-infrared spectroscopy study Ziyan Wu (Boston, MA, USA) - Online presentation
  17:30-18:30	L9 Sex differences in chronic visceral pain Emeran Mayer (Los Angeles, CA, USA)
  20:00-21:30	Dinner in the small Cloister
  21:30	W1 Debate teams

   

• Tuesday, 14 June
  9:00-10:00	L10 Neuroimmune Interactions in Models of Rheumatoid Arthritis Marzia Malcangio (London, United Kingdom)
  10:00-10:15	S17 Endoplasmic reticulum stress sensor in chemotherapy-induced peripheral neuropathy (CIPN) Miriam M. Fonseca (Winston-Salem, NC, USA)
  10:15-10:30	S18 Immune cells in the dorsal root ganglia could be important contributors to sex differences in pain biology of the rheumatoid arthritis model CAIA Zerina Kurtović (Solna, Sweden)
  10:30-11:00	Coffee break
  11:00-11:15	S19 Role of CCL2 in neuropathic pain Atlante Mendes (Ribeirão Preto, Brazil)
  11:15-11:30	S20 Contribution of TTX-resistant NaV channels to the generation of membrane potential instabilities in mouse trigeminal neurons Enrique Velasco Serna (Leuven, Belgium)
  11:30-12:30	L11 Modulation of sensory transduction by subthreshold membrane potential instabilities Karel Talavera (Leuven, Belgium)
  13:00-15:00	Lunch break
  15:00-16:00	W2 Behavioral studies on thermal, mechanical, and spontaneous pain Federico Montechiaro & Mauro Uboldi (Ugo Basile Srl, Gemonio, Italy)
  16:00-16:15	S21 Young patients with cerebral palsy exhibit an aberrant somatosensory profile and exaggerated experimentally induced hyperalgesia suggesting a central sensitization subtype of neuropathic pain Paul Merz (Mannheim, Germany)
  16:15-16:30	S22 Pain-depressed climbing in male and female mice as a tool for analgesic drug development Edna J. Santos (Richmond, VA, USA)
  16:30-17:00	Coffee break
  17:00-17:15	S23 Implications for inflammation and host-microbiome interactions in neurogenic bowel-associated dysfunction and pain after spinal cord injury Adam Willits (Kansas City, KS, USA)
  17:15-17:30	S24 Parabrachial modulation of sensory and motivational behaviors in mice Yu-Ting Cheng (Boston, MA, USA) - Online presentation
  17:30-18:30	L12 Gut visceral pain: triggers and pathways Nathalie Vergnolle (Toulouse, France)
  20:00-21:30	Dinner in the small Cloister
  	W3 "Pontignano under the stars" Vincenzo Millucci and Alessandro Marchini

   

• Wednesday, 15 June
  9:00-10:00	L13 Hormonal modulation of pain Anna Maria Aloisi (Siena, Italy)
  10:00-11:00	W4 "Trio" Emeran Mayer, Peter Holzer, Nathalie Vergnolle
  11:00-11:30	Coffee break
  11:30-12:30	L14 Control of pain and inflammation: the model of tonic immobility Giancarlo Carli (Siena, Italy)
  13:00-15:00	Lunch break
  	Afternoon and Evening: excursion to Siena old town

   

• Thursday, 16 June
  9:00-10:00	L15 Microbial approaches to treat visceral pain Nathalie Vergnolle (Toulouse, France)
  10:00-11:00	L16 Ethics in pain: treatment of babies in pain Carlo V. Bellieni (Siena, Italy)
  11:00-11:30	Coffee break
  11:30-11:45	S25 Efficacy of acupuncture and heat-sensitive moxibustion versus electroacupuncture for trigeminal neuralgia Katrina R. Hamilton (Baltimore, MD, USA)
  11:45-12:45	L17 QST: from small fiber to central pain processing Ofrit Bar-Bachar (Medoc, Ramat Yishai, Israel)
  13:00-15:00	Lunch break
  15:00-16:30	W5 Pain labs Ofrit Bar-Bachar (Medoc, Ramat Yishai, Israel) & Peter Reeh (Erlangen, Germany)
  16:30-17:00	Coffee break
  	Molteni Symposium
  17:00-18:00	L18 Opioid induced constipation (OIC) Flaminia Coluzzi (Rome, Italy)
  18:00-19:00	L19 Cancer Pain and Breakthrough cancer Pain (BTcP) Flaminia Coluzzi (Rome, Italy)
  20:00-21:30	Dinner in the small Cloister

   

• Friday, 17 June
  9:00-10:00	L20 TRP channels in migraine, neuropathic and cancer pain Pierangelo Geppetti (Florence, Italy)
  10:00-10:30	W6 Debate 1 Irritable bowel syndrome has no organic cause. YES or NO?
  10:30-11:00	Coffee break
  11:00-11:30	W7 Debate 2 Fecal transplant can change life in health and disease. YES or NO?
  11:30-12:00	W8 Pain Quiz
  12:00-15:00	Lunch break
  15:00-19:00	Rapolano Terme SPA: Antica Querciolaia
  20:00	Dinner at the Certosa

   

• Saturday, 18 June
  	Departures